Taiwanese Billionaire Establishes Richer-Than-Nobel Prizes

first_imgTaiwanese businessman Samuel Yin has endowed a new science prize that not only gives bigger cash awards than the Nobel Prizes, but supports research as well. Individuals or institutions that have demonstrated what judges deem to be the most creative and influential research will receive about $1.36 million in each of four fields; an additional $341,000 will support recipient-proposed plans for research and talent development in related fields for 5 years. The combined $1.7 million tops the Nobel Prize, which for 2012 was about $1.2 million. Announced at a press conference today in Taipei, the Tang Prize, named after China’s Tang Dynasty, which Yin admires as a golden age for Chinese civilization, will be awarded biennially for work in sustainable development, biopharmaceutical science, sinology, and rule of law. Yin, who is endowing the Tang Prize Foundation with about $102 million, hopes “the prize will encourage more research that is beneficial to the world and humankind, promote Chinese culture, and make the world a better place,” according to a press release. Yin made a fortune in real estate, finance, and retail investments, and is worth about $3 billion, according to Forbes magazine. Academia Sinica, which oversees Taiwan’s premier research labs, will be responsible for the nomination and selection process. The first prize announcement is slated for July 2014. Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*) The Tang Prize lengthens the list of rich science prizes funded by Asian philanthropists. Run Run Shaw, a Hong Kong media mogul, in 2002 established the Shaw Prize, which annually confers $1 million for work in astronomy, life science and medicine, and mathematical sciences. Three other major science prizes in Japan hand out about $550,000 to each winner annually: Kyoto Prize. Launched in 1984 by Kazuo Inamori, founder of specialty ceramics maker Kyocera, it honors advanced technology, basic sciences, and arts and philosophy. Japan Prize. Backed by Konosuke Matsushita, founder of Panasonic Corporation, the award is given in in two broad scientific fields. In 2012, those were (1) environment, energy, and infrastructure and (2) health care and medical technology. Blue Planet Prize. The 20-year-old award given by the Asahi Glass Foundation recognizes premier environmental research.last_img read more

New painkillers could thwart opioids’ fatal flaw

first_img When people die from overdoses of opioids, whether prescription pain medications or street drugs, it is the suppression of breathing that almost always kills them. The drugs act on neuronal receptors to dull pain, but those in the brain stem also control breathing. When activated, they can signal respiration to slow, and then stop. The results are well-known: an epidemic of deaths—about 64,000 people in the United States alone last year.Countering this lethal side effect without losing opioids’ potent pain relief is a challenge that has enticed drug developers for years. Now, for the first time, the U.S. Food and Drug Administration (FDA) in Silver Spring, Maryland, is considering whether to approve an opioid that is as effective as morphine at relieving pain and poses less risk of depressing breathing.Trevena, a firm based in Chesterbrook, Pennsylvania, announced on 2 November that it has submitted oliceridine, an intravenous opioid meant for use in hospitalized patients, to FDA for marketing approval. The drug, which would be marketed under the name Olinvo, is the most advanced of what scientists predict will be a growing crop of pain-relieving “biased agonists”—so called because, in binding a key opioid receptor in the central nervous system, they nudge it into a conformation that promotes a signaling cascade that kills pain over one that suppresses breathing. And in a paper out this week in Cell, a veteran opioid researcher and her colleagues unveil new biased opioid agonists that could surpass oliceridine, though they haven’t been tested in people yet.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*) Bias toward breathing A new generation of opioids aims to stall the signaling that is thought to shut down the lungs during overdoses. New painkillers could thwart opioids’ fatal flaw SPENCER PLATT/GETTY IMAGES Biased opioids Less respiratory depressionand constipation V. ALTOUNIAN, K. SUTLIFF/SCIENCE Classical opioids When traditional opioids—such as morphine, fentanyl, and heroin—activate the receptor, that also attracts an intracellular protein called β-arrestin2. It tamps down G-protein signaling, so that the message doesn’t remain indefinitely “on.” But β-arrestin2 also helps produce the respiratory suppression and constipation that are hallmark side effects of opioids.Beginning 18 years ago, Bohn and her colleagues showed that, in mice engineered to lack β-arrestin2, morphine’s pain relief was stronger and longer-lasting and its main side effects were dramatically reduced. The mechanism by which β-arrestin2 leads to an opioid’s unwanted effects remains unclear. But it seemed to many researchers that if drugs could be created that nudged the µ-opioid receptor into a conformation that shut down β-arrestin2 recruitment while turning on G-protein signaling, they might deliver opioids’ unparalleled pain relief without those side effects.In the new study, Bohn’s group used cell signaling assays on a library of µ-receptor-activating compounds to find a few with hints of a bias toward G-protein signaling. Based on the structural features of those leads, they tweaked the compounds to create scores that were more heavily biased. They chose six to study in mice, and discovered all had effective antipain activity. As important, the greater the compound’s bias for G-protein-signaling, the fewer breathing problems it produced in the animals.The study is “very rigorous and formalized. And it’s pretty remarkable. Essentially the more G-protein biased, the less respiratory depression. In other words, the safer,” Roth says. The paper “is a tour de force,” for its labor-intensive validation of concepts that had only been inferred from smaller studies, says molecular pharmacologist Gavril Pasternak of the Memorial Sloan Kettering Cancer Center in New York City.Other academic groups are chasing biased opioids. A team including Roth and Brian Shoichet, a chemist at the University of California, San Francisco, who uses computer simulations to find new drugs, last year published details of a powerfully G-protein-biased µ-receptor agonist, PZM21. It kills pain in mice and doesn’t depress breathing. In its 2016 paper, which appeared in Nature, the group also reported that PZM21 appeared to be less rewarding in mice. That suggests it could be less addictive in people, though further studies are needed, says Roth, who holds founder stock in a San Francisco startup, Epiodyne, aiming to develop the compound further.Some doubt that PZM21 will turn out to be less prone to abuse in humans. That suggestion doesn’t line “up with the basic science and certainly does not describe our own data on Olinvo,” says Jonathan Violin, a molecular pharmacologist who co-founded Trevena and is now one of its vice presidents.For biased opioids in general, “The $64,000 question is: What about dependence?” says Robert Lefkowitz, a biochemist at Duke University in Durham, North Carolina, who shared the 2012 Nobel Prize in Chemistry for work on G-protein-coupled receptors, and who co-authored Bohn’s first paper on β-arrestin2 knockout mice. Lefkowitz, who owns founder shares in Trevena and stands to make money if Olinvo succeeds, says there is little evidence that tamping down β-arrestin2 will blunt the agonizing physical withdrawal symptoms that set in when someone tries to kick an opioid habit.Bohn plans to evaluate the addictiveness of her stable of compounds in an upcoming study. But first, she is probing whether heavily G-protein-biased opioids can slay another bugbear of these medicines: tolerance, which is the need for increasing, and ever-riskier, doses of a drug to achieve the same amount of pain relief. “So far,” she reports, “it’s looking really promising.” Oliceridine G-proteinsignaling Extracellularcenter_img Powerfulpain relief By Meredith WadmanNov. 16, 2017 , 12:00 PM Because opioids can shut down breathing, overdoses are often fatal without medical intervention. Powerfulpain relief G-proteinsignaling “There are many groups creating [such] biased agonists. And one of them is going to get it right,” says Bryan Roth, a molecular pharmacologist at the University of North Carolina in Chapel Hill. “To have a drug you can’t die of an overdose with would be a huge lifesaver for tens of thousands of people every year.”Trevana’s compound is by far the closest to the finish line, having been through clinical trials. The firm has had setbacks, however. In phase III trials in postsurgical patients reported in February, oliceridine proved to be as effective a painkiller as morphine, and quicker to act. But although a low dose of it caused less respiratory suppression and fewer other side effects than morphine, those improvements didn’t reach statistical significance for higher doses.The competition aims to catch up quickly. Last month, Mebias Discovery in Philadelphia, Pennsylvania, presented data on two new biased opioids that protected breathing in rats even at four times the effective painkilling dose. It hopes to begin human trials of one of them as soon as 2019.For most of these early-stage drugs, developers haven’t assessed just how selectively they trigger the painkilling pathway over respiratory suppression. Nor have they shown conclusively that the molecular bias matters—that the more biased a compound toward triggering the painkilling pathway, the less the risk of respiratory suppression. But the Cell study this week has done both, at least in mice.In that work, neuroscientists Laura Bohn, Cullen Schmid, Thomas Bannister, and their colleagues at the Scripps Research Institute in Jupiter, Florida, developed several pain-killing-biased compounds from among scores that bind the µ-opioid receptor. Activating this protein, which is embedded in neuronal cell membranes, leads to either pain relief or respiratory depression depending on the brain circuit to which it belongs. The molecule is known as a G protein-coupled receptor because it triggers so-called G proteins to bind to the inner side of a receptor and start a signal cascade. Morphine Respiratory depressionand constipation Cell membrane Intracellularlast_img read more

Despite scathing harassment report, UNAIDS board gives agency head a reprieve for now

first_img By Jon CohenDec. 13, 2018 , 4:05 PM DENIS BALIBOUSE/REUTERS Michel Sidibé A board that oversees the Joint United Nations Programme on HIV/AIDS (UNAIDS) in Geneva, Switzerland, the global command center in the fight against the infectious disease, has resisted calls to immediately recommend the firing of the agency’s executive director in the wake of a report that found UNAIDS rife with harassment, bullying, and abuses of power. The Programme Coordinating Board, which finished a meeting today that included discussions of the report, instead established a working group to further consider the allegations and criticisms. (The board itself cannot fire the UNAIDS head, but it can recommend the action to the United Nations.)UNAIDS Executive Director Michel Sidibé, who initiated the review that ultimately called for his ouster, spoke at the board’s meeting and asked to stay on through June 2019 to oversee an “agenda for change” that his management team has drafted in response to the report. “We don’t have a moment to lose in moving forward our management response,” Sidibé said in a statement. “I look forward to an inclusive, transparent, and open dialogue and collaboration with staff in shaping a new UNAIDS.”center_img It’s too early to say, however, whether Sidibé’s job is safe until next summer. Sweden, UNAIDS’s second largest donor, announced earlier this week that it would freeze support for the agency until Sidibé leaves. Other donors—including the United States, the largest donor—have yet to take such a public stance.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)In the long run, the future of UNAIDS itself may be in jeopardy, says Sten Vermund, who heads the Yale School of Public Health. The panel contends that UNAIDS’s problems stem from its unique position within the United Nations system, which has led to it being “governed in a way that has produced a vacuum of accountability.” Vermund suggests this could lead to soul searching about whether UNAIDS should continue to exist as a special agency. “Is UNAIDS serving the purpose for which it was formed, and could those functions be better subsumed in the [World Health Organization]?” he wonders. “Ultimately, you have to ask that question.” Despite scathing harassment report, UNAIDS board gives agency head a reprieve for now last_img read more

IPL match fixing: BCCI moves Supreme Court seeks transcripts of tapes

first_imgThe BCCI today moved an application before the Supreme Court seeking transcripts of audio tapes containing statements of Board President N Srinivasan and Indian captain Mahendra Singh Dhoni, recorded by the Mukul Mudgal Committee which probed allegations of IPL spot and match fixing.The plea was mentioned before a bench headed by Justice A K Patnaik which posted the matter for hearing on April 11.In the application BCCI has also sought the transcripts of statements by Sundar Raman, the Chief Operating Officer of IPL.The application was mentioned by Senior Advocate C S Sundaram who was appearing for BCCI.The counsel told the bench that they need the transcript to prepare themselves for the matter which is pending before the Supreme court.Earlier, the Supreme Court had proposed the name of veteran cricketer and commentator Sunil Gavaskar to head the Board during pendency of the case in the apex court.last_img read more

Nominations for the Second Edition of the Indian Sports Honours (ISH) announced

first_imgAdvertisementThe nominations for the Second Edition of the Indian Sports Honours (ISH) has been announced.  ISH an initiative by Virat Kohli and Sanjiv Goenka felicitates and Honour sportsperson for their achievements, performance and contribution to the sport. Athletes with tremendous achievements will be honoured on 16th February 2019 in Mumbai across 17 categories, including one Life Time Achievement Honour.Winners for 11 categories will be selected by the ISH Jury, which are the Jury Honours across categories like Emerging Sportsperson, Differently Abled Sportsperson, Sportsperson of the Year and more. The ISH Jury including Mr. Sanjiv Goenka, Pullela Gopichand, Abhinav Bindra, Sardar Singh, Mahesh Bhupathi, PT Usha and Anjali Bhagwat will finalise the winners. The nominations in each category were shortlisted by 200 journalists from the Sport Journalists Federation of India and the process was overseen and validated by Ernst & Young.There are also six Star Sports Popular Choice Honours, winners for which will be decided by the people. Fans can vote for their favourite athletes in the following categories on Twitter through the ISH handle (@SportsHonours) until 16 February 2019. Advertisementlast_img read more

Brazil reach the semis of Copa America with shootout heroics against Paraguay

first_imgAdvertisementThe Brazilian National side were able to beat Paraguay in the semifinal of the Copa America. The game went direct to the penalty shootout after end of 90 minutes. The defensive unit of Paraguay frustrated Brazil through out the whole match. Paraguay also had the psychological advantage in the tiebreaker as they knocked out the Selecaos previously from the same position in 2011 and 2015.The coach of Brazil, Tite fielded his side with the usual 4-2-3-1 formation. Casemiro was missing the match with two yellow cards already in the tournament. The ball possession was under the control of the Selecaos from the very first minute of the match. However, they were not able to score due to lack of finishing ability of the attackers.Paraguay were playing rough and tough football and their defensive unit stayed strong till the end of the regulation time. In the first half, the Selecaos tried to slow things down. They were not able to create many opportunities with having 65 percent of ball possession.In the second half, the scenario changed after Fabian Balbuena left the field at the 58th minute of the match. Brazil kept of pressing the defense of Paraguay. Gabriel Jesus missed an open chance. Roberto Firmino was also not at his best in this match. The match ended with a scoreline of 0-0 after the end of 90 minutes.In the penalty shootout, Alisson Becker saved the first penalty taken by Gustavo Gomez. Roberto Firmino’s penalty was not on target for Brazil; but Derlis Gonzalez missed the last one for Paraguay. Gabriel Jesus kept his calm to help Brazil going through to the semifinal of Copa America. Brazil will face either Venezuela or Argentina in the next round of the competition.South Korea break Indian hearts in Azlan Shah Cup final over penalty shootouts Advertisementlast_img read more

Yuvraj Singh asks MS Dhoni: Now that you’re not captain, will you hit more sixes?

first_imgContrary to popular perception, Team India stalwarts Mahendra Singh Dhoni and Yuvraj Singh do share a very good rapport on and off the cricket field. Their friendship was very much evident on Tuesday as India A played against England in the first warm-up match at the Brabourne stadium in Mumbai. (Good to see huge turnout for warm-up game, it shows their love for me: Dhoni)Even though Dhoni’s final match as captain ended in disappointment as England won by 3 wickets, the mood in the Indian camp is still upbeat. Yuvraj posted a video on social media after the match got over in which he asked a couple of very interesting questions to Dhoni, who answered each question in his typical manner. (Watch: Fan rushes out to touch MS Dhoni’s feet at Brabourne Stadium)Yuvraj asked Dhoni about his journey as India captain to which he said,” the journey has been good, fantastic. It’s good to have players like you (Yuvraj) the job becomes much more easier. Enjoyed my 10 years and hopefully I’ll enjoy more whatever I have.” (Vintage Dhoni, Yuvraj shine for India A) Yuvraj paid tribute to Dhoni by saying that he’s been one of the best captains ever and that he had an amazing time playing under him. Dhoni interrupted Yuvraj in between and thanked him for the six sixes that he hit in the 2007 World T20 where Dhoni was at the other end and had the best seat in the house. (Dhoni deserves every bit of respect he’s getting: Sourav Ganguly to India Today)advertisementWell done @msdhoni on your career as captain ! 3 major wins 2 w cups ????????????? time to unleash the old dhoni????? pic.twitter.com/7WXdre9qJU yuvraj singh (@YUVSTRONG12) January 10, 2017Yuvraj had said a few days ago that he is looking forward to partnering with Dhoni once again in the middle-order and play fearless cricket like the way they used to before. Now that the burden of captaincy is no longer on Dhoni’s shoulders and with an in-form Virat Kohli leading the side, it is expected that Dhoni will bat up the order and play an attacking brand of cricket.Dhoni smashed 68 off 40 balls yesterday while Yuvraj scored 56 off 45 balls to power India A to 304/4 in 50 overs. Unfortunately it was the bowling attack which let them down as England reached the target with 3 wickets and an over to spare.But it was Dhoni and Yuvraj’s batting which was the highlight of the match. Both looked calm and composed at the crease and played freely. Even though they couldn’t bat together for long, they made sure to entertain the crowd by hitting sixes and fours at will. Shikhar Dhawan also got some much needed runs under his belt and scored 63 runs off 84 balls.Dhoni, Yuvraj and Dhawan’s form will be crucial for India when they take on England in the upcoming three-match ODI series and in the following three T20Is from January 15.last_img read more

Governor, CM congratulate Ker team for winning Santhosh Trophy

first_imgThiruvananthapuram, Apr 1 (PTI) Kerala Governor Justice (ret) P Sathasivam and Chief Minister Pinarayi Vijayan were among those who congratulated the state football team for winning the Santhosh Trophy defeating Bengal today. Sathasivam in a message said the victory after a gap of 14 years had re-established Keralas supremacy in Indian football. Vijayan said victory was not only a proud moment but also inspiring. State Sports Minister A C Moideen and Leader of the Opposition in the assembly Ramesh Chennithala also congratulated the Kerala team on the victory. Kerala had edged out Bengal via the tie-breaker in the final held at Kolkata. PTI JRK SSlast_img

ESPN Computer: Only 2 Teams Have A Serious Chance At The National Title

first_imgDabo Swinney celebrates winning it all with his wifeTAMPA, FL – JANUARY 09: Head coach Dabo Swinney of the Clemson Tigers celebrates with his wife, Kathleen Swinney, after defeating the Alabama Crimson Tide 35-31 to win the 2017 College Football Playoff National Championship Game at Raymond James Stadium on January 9, 2017 in Tampa, Florida. (Photo by Tom Pennington/Getty Images)The 2018 college football season hasn’t hit November yet, so we’re still a ways away from talking about the national title.ESPN’s computer, though, believes it’s already a two-team race.FiveThirtyEight’s computer projections believe just two teams have a legitimate chance at winning the national championship.Those two teams:AlabamaClemsonAlabama is given a 30 percent chance of winning the national championship, while Clemson is given a 25 percent chance.Those two teams are the only two teams given a more than 10 percent chance of winning the national championship.You can view the full projections here.last_img read more

BG Group Starts Up Sixth FPSO in Santos Basin, Brazil

first_imgzoom British multinational oil and gas major BG Group has reported first oil from the Cidade de Itaguaí floating, production, storage and offloading (FPSO) vessel, the sixth unit to start production in the Santos Basin, offshore Brazil.The FPSO will produce from the Iracema North area of the Lula field in the Petrobras-operated BM-S-11 block.Anchored 240 km off the coast of Rio de Janeiro, the Cidade de Itaguaí is approximately 2,220 metres above the ocean floor.This is the second leased FPSO deployed on the Iracema development, expected to double the gross production capacity to 300 thousand barrels of oil per day and 16 million cubic metres of natural gas per day from the area. The FPSO will also be able to store 1.6 million barrels of oil.BG Group has a 25% interest in Block BM-S-11 (Petróleo Brasileiro S.A., operator, 65% and Petrogal Brasil S.A., 10%). BG Group also has a 30% interest in Block BM-S-9 (Petróleo Brasileiro S.A., operator, 45% and Repsol Sinopec Brasil 25%).last_img read more

Alberta says it will invest in Indigenous Peoples to build green economy

first_img(Alberta Premier Rachel Notley waves after her government’s swearing-in. APTN/file)Brandi Morin APTN National NewsThe Alberta Minister of Environment said her government is committed to ensuring Indigenous People aren’t left out of plans to kick-start the creation of a green economy.Environment Minister Shannon Phillips stressed Alberta is making a priority of making “meaningful” strides within Indigenous communities on the renewable energy front.She said that the governments’ nation-to-nation relationship ambitions includes building capacity with Indigenous Peoples in order to engage in meaningful participation and consultation.“We remain committed to ensuring that we are building capacity in Indigenous communities so that we can build an energy economy that comprises all of energy, not just oil and gas,” said Phillips.Funding for capacity building spills out into economic opportunities that she said the government wants to ensure Indigenous People have equal access to in the expected renewable energy boom.“What we want to make sure of is, as we build a greener economy, one based on renewable energy that the new economy doesn’t look like the old,” she said. “In that it does not replicate the social and economic exclusion of Indigenous people that we’ve seen for generations in Alberta and that we are actually meaningfully ensuring economic growth, prosperity, and social inclusion throughout our process.”No specific amount of money is set aside as of yet for the task. Phillips said they’re still in talks with chiefs and others within governments on how to move forward. However, she did make mention that conversations on resource revenue sharing are happening.The province recently announced their new climate change strategy bannering itself as a global leader in climate action.Recommendations by an independent review panel included a section on Aboriginal components which Phillips said she fully supports.There are also plans to focus on incorporating Indigenous knowledge into the provinces climate change action plan.“From my department in Environment that has a lot to do with how we ensure that traditional and ecological knowledge is appropriately integrated and used to plan resource development and communities,” said Phillips. “Those are pieces that are very important to my department in environment as we work through a lot of regional planning process and land use frameworks to make sure that not only are we getting the traditional ecological knowledge parts—not only making sure that those are in order—but also to ensure that we’ve got adequate capacity in place for traditional land use, co-managements of natural areas and other ways that we know that we can do better than the previous Conservative government.”Phillips added that she is serious about implementing the United Nations Declaration on the Rights of Indigenous Peoples (UNDRIP) into her portfolio as mandated to all Alberta NDP MLA’s by Premier Rachel Notley last summer.Phillips is expected to join Notley at the UN climate conference in Paris that began Monday. Phillips said she will be supporting local Indigenous voices at the international level.“Because I think that that’s an important way that Alberta and Canada can ensure that we are moving forward in ways that are respectful of Treaty and respectful of the new economy that we’re all building together.”bmorin@aptn.ca@songstress28last_img read more

Huawei Wants Morocco to be the First Country to Launch 5G…

Rabat – Huawei, a global provider of information and communications technology infrastructure and devices, outlined the goal for its Moroccan operations at the 9th annual North African suppliers conference in Skhirat, south of Rabat today, Thursday July 18.“We are the [world] leaders in 5G, and we want to be the leader in Morocco,” said Chakib Achour, the marketing and strategy director of Huawei in Morocco.“We want the Kingdom to be the first to launch 5G in Africa,” he specified. According to Achour, the company is now only waiting for the green light from the government. 5G is the new generation of mobile internet connectivity, which promises much faster data upload and download speeds, wider coverage and more stable connections.Internet is important to Moroccans. According to a report released this week by the Moroccan National Telecommunications Regulations Agency (ANRT), access to the internet by Moroccan households has increased three-fold over the last eight years. 74.2% of households are now equipped with internet.Read Also:Telecommunications Report Finds 76% of Moroccans Use SmartphonesAccording to ANRT, the leading reason behind the need for an internet connection is  “entertainment” (including games and social networks), with Whatsapp and Facebook being the most used apps.  Moroccan telecommunications provider Inwi announced in March that it was ready to launch 5G. “5G is a reality for Inwi. It is a reality that we anticipated and prepared for through modernising out infrastructure […]. Inwi has modern and agile infrastructure, capable of adapting to all technical evolutions, now and in the future,” declared Fadoua Laaroussi, the performance director at Inwi, in a press release.Huawei has stated that Inwi is its “strategic partner in the North Africa region.”“Inwi is the first operator who has signed an agreement with Huawei for the 5G pilot projects […],” Huawei marketing vice-president Eric Liu said.Huawei is not the only player on the Morocco 5G field. In March, Huawei competitor Ericsson organised a live 5G demonstration at Maroc Telecom headquarters in Rabat, showcasing the technology’s capabilities.Huawei is firmly present in Morocco, with, according to Achour, an annual revenue of MAD 3 billion, reports Moroccan news source Aujourd’hui le Maroc. Huawei works with the three major local telecommunication providers: Maroc Telecom, Inwi, and Orange.Expansion into Africa might be Huawei’s next big move, as its future trade relations with the US are currently uncertain. In early May, US President Donald Trump put Huawei on the “entity list,” on the basis of national security concerns, as part of a complex diplomatic battle between the US and China. The list essentially bars US companies from trading with Huawei without a special license. In early July Trump reportedly eased sanctions, although confusion remains on future trade relationships. read more

Small businesses in Armenia to receive boost from UN rural development fund

The United Nations International Fund for Agricultural Development (IFAD) announced today that it will spend over $12 million for a new project in Armenia to help develop microenterprises with potential for rapid growth.The Farmer Market Access Programme will provide loans to rural and peri-urban Armenians to develop profitable on- and off-farm small businesses who do not qualify for conventional bank loans.“Once they are able to access credit, poor rural producers will have many more opportunities to develop profitable and commercially viable products and services all along the market value chain,” said Henning Pedersen, IFAD’s country programme manager for Armenia.An increase in the number of rural enterprises will also spur job creation, he added.IFAD will contribute $11.9 million in loans and $500,000 in grants, while the OPEC Fund for International Development will supply $10 million. Other co-financers for the $32.2 million programme include the Armenian Government and financial institutions.Applicants for the project’s funds must show that their prospective enterprise will generate sustainable income growth among target groups, including farmers as well as unemployed, under-employed and self-employed people. Preference will be given to those who engage women as suppliers and employees.The project also aims to arm participants with the knowledge, technology and infrastructure to help them profit from domestic and export markets.Improving access to roads, small-scale irrigation and village gas supplies are also emphasized by the programme, with participants contributing a minimum of 10 per cent in cash or kind to offset infrastructure costs.In an innovative move, the project’s main financing instrument will be a venture capital fund, the Fund for Rural Economic Development in Armenia (FREDA). 8 January 2008The United Nations International Fund for Agricultural Development (IFAD) announced today that it will spend over $12 million for a new project in Armenia to help develop microenterprises with potential for rapid growth. read more

Opinion Greatest regret as an Ohio State student – not watching Kyle

OSU then-sophomore Kyle Snyder gets his hand raised during a meet against Nebraska at St. John Arena on Jan. 17. Credit: Lantern file photoThere are more lies than truths told at family functions. From dinner to shooting the bull afterward, most of the stories shared never happened, but they’re harmless lies.In my family, that “shooting the bull” devolves into the men sitting around trying to prove who knows best in remembering some of the most dominant Ohio State sports legends in their lifetimes.They remember watching from the nosebleeds, or through their first television, all the miraculous things Archie Griffin, Eddie George, Jerry Lucas, Jimmy Jackson and Scoonie Penn did while at Ohio State.I’m in my final year as an undergraduate at Ohio State, and I imagine decades from now when I partake in the debate of the greatest athletes to grace Columbus, it’ll go something like this: “Let me tell you about the most complete, dominant athlete in the world who won a gold medal at the Olympics while he wrestled in college.“And let me tell you how I never saw Kyle Snyder in person and I didn’t watch him nearly enough on TV.”When you’re told college will be “the best years of your life,” it’s generally referring to the experiences gained, lessons learned and friends made that last a lifetime. I’ve had plenty of those, and outside of trivial matters, I wouldn’t want my time at Ohio State to be any different than what it has been: except for a chance to watch Snyder every moment I could have.All of that is the truth.Snyder will wrestle for the final time at home as an Ohio State Buckeye Sunday in front of what might be a sellout crowd at the Schottenstein Center. And it will be another opportunity — like many other Ohio State students — I will miss seeing a man who is sure to be on the Mount Rushmore of Ohio State athletes, with the likes of Jesse Owens and Jack Nicklaus.It would take me more than this entire column to list his individual achievements, so a quick glance at his university bio should suffice for why Snyder will be remembered at Ohio State as one of its all-time legendary athletes.OSU junior heavyweight Kyle Snyder lifts Wisconsin’s Connor Medbery before slamming him to the mat for a takedown in the heavyweight finals of the 2017 NCAA Division I Wrestling Tournament in St. Louis, Missouri. OSU placed second, behind Penn State. Credit: OSU AthleticsIf there’s one moment that tipped the scales toward Snyder’s improbable career, it was becoming the youngest world champion in USA wrestling history during summer 2015, between his freshman and sophomore seasons. That following spring, he beat two-time defending national champion Nick Gwiazdowski at Madison Square Garden to capture his first NCAA title.All he did a few months later was win a gold medal as a 20-year-old at the Olympics in Rio De Janeiro.That should’ve been more than enough to convince me that Snyder had to be seen in person, or I’d regret it for the rest of my life. Only one other athlete from Ohio State had gone to the Olympics while a student before Snyder — it was Lucas. He was clearly dominant on the international stage, so why would I deprive myself from watching an Olympic champion in person, while I had the chance?That’s just not something a student gets to do at his own school.Yet, when given the chance again, when he announced he would return for his senior season, I didn’t give it a second thought outside of, “Oh, that’s cool.” The mistake was mine for not watching Snyder.I never paid attention to wrestling before I enrolled at Ohio State — and I still don’t. That’s not to say that I don’t find the sport entertaining or fascinating — I do. Wrestling season aligns with college basketball, which has always been my sport of choice for entertainment. However, a casual sports fan should be able to appreciate Snyder’s greatness and unequivocal skill at the collegiate level. A casual fan should have taken the time to sit in a mostly empty arena and watch Snyder’s unparalleled display of power.I watched him on TV win gold and show off the American flag draped on his back to the entire arena in Rio. Just last week, I stopped what I was doing to watch Snyder finish a fall at Rutgers on TV. It’s honestly quite funny watching Snyder give his opponents false hope by allowing them to stand up and earn a point for an escape before Snyder buries them again.But here I am on the eve of Snyder’s final match in Columbus with Ohio State, knowing I won’t be in attendance tomorrow because I’ll be heading to a concert in Kentucky. The little I know to be true about him will sound like false tales to whomever will hear me talk about all Snyder accomplished in his time at Ohio State.“Yes, all of that is true,” I will say. “And I missed most of it.” read more

Drinkdrivers have fear of missing out says campaign to target men who

first_imgDecember will be epic. A second drink before driving doubles your chances of being in a fatal collision & missing out on it all #FOMOpints pic.twitter.com/NEMibKlj9d— THINK! road safety (@THINKgovuk) December 1, 2016 Road safety minister Andrew Jones said the crime, which kills five people every week, “destroys families and ruins lives”.”This Christmas we are specifically targeting the biggest perpetrators of this devastating crime – young men. But our message to everyone remains the same: don’t drink and drive,” he said.The campaign coincides with a month-long police operation to combat drink and drug driving during the festive period.Forces around the country will target known hotspots to detect people who are on the road illegally.In December last year, police forces administered 110,226 breath tests, of which 5,543 were positive, failed or refused, according to the National Police Chiefs’ Council (NPCC).Some 1,888 drug screening tests were conducted during the same period, with almost half turning out positive. “Don’t #drive under the influence of #drink or #drugs. Even a very small amount can affect your ability to drive safely.” @ChiefGlosPolice— NPCC (@PoliceChiefs) December 1, 2016 Drink-driving is fuelled by the “fear of missing out”, the government has suggested, as it launches a campaign targeting young men who commit the crime to avoid not being able to go on a night out.Nearly two-thirds (62 per cent) of all drink-drivers who die in collisions are young men, according to Department for Transport figures that also showed that 20 per cent of the age group had driven after having two or more drinks, despite this doubling their chances of being involved in a fatality.Their “fear of missing out” – or FOMO – will be targeted in a new advert that will be released every day on Facebook, Twitter and Spotify during the month-long THINK! campaign launched on Thursday.The adverts, which show a pint of beer with FOMO written on it, aim to make it clear to young men that they have plenty to live for the following day, which they may not see if they choose to have a second drink.center_img Research by price comparison website MoneySuperMarket found that for the second year running Crewe has the highest proportion of motorists with drink or drug driving convictions.The Cheshire town has a rate of 1.66 convictions per 1,000 drivers, according to the study. Llandrindod Wells, Powys, was ranked second, followed by Hereford in third.London dominated the list of postcodes with the lowest conviction rates, with the north west of the capital having just 0.53 drink or drug drivers per 1,000.CORRECTION: This article originally attributed to MoneySavingExpert.com the finding that Crewe in Cheshire has the highest proportion of motorists with drink or drug driving convictions. In fact, this was a finding of research by Moneysupermarket.com. MoneySavingExpert.com is a consumer personal finance website, not a “price comparison site”, as originally stated. We have amended the article accordingly.  Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings.last_img read more

BC leaders raise key issues with minister

first_imgSecretariat: A team of BC leaders led by R Krishnaiah, the former MLA and president of BC Welfare Association, met Minister for Welfare Koppula Eshwar and held discussion on various BC issues on Thursday.Speaking to media after the meeting, Krishnaiah said that they appealed to the minister to sanction full fee reimbursement to BC students who were pursuing engineering and other professional courses. He demanded that government to withdraw the criteria of giving fee reimbursement only to those who secured less than 10,000 rank. The minister was also urged to release funds for BC subsidy loans. Also Read – Two Urban forest parks inaugurated in Hyderabad Advertise With Us As many as 5,77,000 BCs applied for BC subsidy loans given through BC Corporation but their applications had been kept pending. He said that they urged the minister to see that loans were sanctioned. Other demands made during the meeting were: hike in the scholarships being given to BC students; coaching of BC students for civil services and other exams at reputed private coaching institutes; and establishment of more BC and ST colleges in the state. A request to start additional sections in BC gurukul schools was also made to the minister, to which the minister assured them that a decision would be taken after consulting the CM.last_img read more

Keep supporting team in transition Dhoni to diaspora

first_img“Keep supporting us. We have a good side, we have a good team. We are in a phase where we are going through a lot of changes but with all due support of yours, we will keep doing well,” Dhoni said in an interaction at the Siddhivinayak Temple here on Sunday.Dhoni, accompanied by his wife Sakshi and former Deputy Chief Minister of Jharkhand Sudesh Kumar Mahto, performed puja at the temple, which is under construction and will open to the public later this year. Also Read – A league of his own!Dressed casually in jeans and t-shirt, Dhoni said it is “a first of a kind” visit to the US for him, since whenever he comes to America, he does not do any public events and only spends private time with family.“I have been to different places. Most of them have been cricket-playing nations like England and Australia. This was a one of a kind (visit) in the US,” he said referring to his public appearance at the temple.He said it was an “eye-opener” for him to see how the diaspora has embraced US culture but at the same time held on to their Indian heritage. Also Read – Domingo named new Bangladesh cricket coach“This is something that is really appreciable. Having immigrated to the US many years ago but to still be 200 per cent Indian and still acknowledge and respect the traditions of the country you are in, I feel is something that everybody needs to learn,” he said.Dhoni also voiced appreciation for the way the first and second generation Indian-Americans have taught their younger children about various aspects of life.“That is something I really appreciate,” he said.Thanking the gathering for the “warm welcome”, Dhoni, who did not interact with the media, said it is an honour for him to be present at the temple. Dhoni noted that cricket is not very popular in the US and on his visits to the country, he often has to explain to those who don’t know about the game that it is similar to baseball.last_img read more

The Priciest Rents in the US Are Somewhere Youve Probably Never Heard

first_imgFebruary 19, 2014 The most expensive city in the United States to rent an apartment does not boast mystically scenic views, particularly trendy locales or soaring cityscapes. Rather, the title is held by a small town in North Dakota called Williston, where rents are rocketing in response to an oil boom.According to a study by Apartment Guide, Williston produces more oil than anywhere else in the country — and it seems as though “apartments can’t be built fast enough” to accommodate the vast number of workers herding to the area, many of whom take home six-figure salaries.Related: From Chickens to Caskets — 8 Unique Rental BusinessesA 700-square-foot, one-bedroom apartment in Williston fetches, on average, $2,394 — which is far more than comparable rentals in San Francisco, $1,776, and New York, $1,504, according to the study.Rents are so high, in fact, that the city recently formed an Affordable Housing Committee, reports Time, in hopes of encouraging cheaper rents.A 2010 census pegged the then-quiet and predominantly agricultural town’s population at 14,700 — a number that has more than doubled today. As a result, infrastructure is being put on a fast track, and many owners of existing properties are increasing their rents.Related: Successful in Pizza? How About Oil ChangesOne particularly popular feature of new residences being built in town? Many feature a “mudroom” in front, says Apartment Guide, where workers can remove their dirty shoes before entering their homes. (After all, in this oil industry hub, the ratio of men to women in Williston is 12 to one.)Located in the northwest corner of the state — on Montana’s border — Williston doesn’t offer much in the way of stimulus, reports ABC News. Its most famous resident is NBA coach Phil Jackson, while the majority of its locals do their shopping at the Walmart Supercenter.Related: 7 Ways Social Media Will Be More Expensive This Year This hands-on workshop will give you the tools to authentically connect with an increasingly skeptical online audience. 2 min readcenter_img Enroll Now for Free Free Workshop | August 28: Get Better Engagement and Build Trust With Customers Nowlast_img read more

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