The future of cancer immunotherapy: your questions, answered

first_img Senior Writer, Biotech Adam is STAT’s national biotech columnist, reporting on the intersection of biotech and Wall Street. He’s also a co-host of “The Readout LOUD” podcast. Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+. First 30 days free. GET STARTED Log In | Learn More Biotech Daily reporting and analysis The most comprehensive industry coverage from a powerhouse team of reporters Subscriber-only newsletters Daily newsletters to brief you on the most important industry news of the day STAT+ Conversations Weekly opportunities to engage with our reporters and leading industry experts in live video conversations Exclusive industry events Premium access to subscriber-only networking events around the country The best reporters in the industry The most trusted and well-connected newsroom in the health care industry And much more Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr. @adamfeuerstein A CT scan of a lung cancer patient. Andy Wong/AP Last week, I hosted an hourlong webinar on future directions for cancer immunotherapy. I focused my talk on three promising avenues of research: checkpoint inhibitors that target the protein called TIGIT; cell therapies utilizing NK, or natural killer, cells; and messenger RNA-based cancer vaccines.The goal with all of these approaches is to increase the number of patients with cancer who can benefit from immunotherapy. By Adam Feuerstein March 29, 2021 Reprints Tags biotechnologycancerSTAT+center_img What is it? What’s included? STAT+ is STAT’s premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond. Adam Feuerstein GET STARTED [email protected] About the Author Reprints The future of cancer immunotherapy: your questions, answered last_img read more

Four Laois projects set to compete in the BT Young Scientist finals

first_img 2020 U-15 ‘B’ glory for Ballyroan-Abbey following six point win over Killeshin Facebook By Dáire McDonald – 8th January 2020 TAGSBT Young Scientist ExhibitionHeywood CSPortlaoise CBSRDS Facebook News Pinterest WhatsApp In Heywood, Evan Hogg is doing his project on ‘An investigation on how physical literacy and parental physical activity levels affects young people’s PAL’ (physical activity level). He is guided by teacher Aodhagan O Suilleabheain.The other two Heywood projects are under the guidance of Sharon Magner.Luke O’Reilly and Sam Farrell’s project is called ‘A statistical analysis on PE taken as an examination subject at leaving certificate level. Will it improve the overall health and well-being of students’.While Orla McCorry’s project is titled ‘Trees on the bog – good or bad for carbon storage?’.The Portlaoise CBS project is called ‘How nitrates affect humans through meat’ and is by Steven Mathai and David Ekpemandu and guided by teacher Helen Dunleavy. Home News Four Laois projects set to compete in the BT Young Scientist finals News Kelly and Farrell lead the way as St Joseph’s claim 2020 U-15 glory GAA Twitter RELATED ARTICLESMORE FROM AUTHOR Four Laois projects set to compete in the BT Young Scientist finals The BT Young Scientist competition finals begin today and Laois have four projects represented across two schools.The BT Young Scientist competition in Europe’s oldest science fair and is now in its 56th year of operation, it sees students from all over the country compete against each other in projects of science and technology.There is three projects from Heywood CS and one project from the Portlaoise CBS. WhatsApp Pinterest The science fair takes begins today and runs until Saturday January 11.The four Laois projects will all have stalls up at the RDS throughput the course of the four days.This is a great achievement by all involved and the best of luck to the Students and their teachers at the fair!SEE ALSO – Range of Hobby Courses starting in Portlaoise Further Education and Training Centre this January Twitter GAA Previous articleAnger as elderly person forced to wait hours for ambulance to arrive to Laois homeNext articleCamogie Association working with Laois to find ‘solution’ to withdrawal decision Dáire McDonald Bizarre situation as Ben Brennan breaks up Fianna Fáil-Fine Gael arrangement to take Graiguecullen-Portarlington vice-chair rolelast_img read more

Improve registration check for investors: FAIR Canada

Facebook LinkedIn Twitter Share this article and your comments with peers on social media Ontario task force looks to boost industry competition On national Check Registration Day, the Canadian Foundation for Advancement of Investor Rights (FAIR Canada) is calling on Canadian regulators to improve investor access to registration information. FAIR Canada said Tuesday that it fully supports the Canadian Securities Administrators’ (CSA) initiative to encourage consumers to check the registration of any firm or individual selling securities or offering investment advice. However, in an open letter to the CSA, it calls upon the provincial regulators to improve the system for examining registration, and other background information. Related news U.S. groups aim to blaze trail to T+1 settlement cycle “We do not believe that regulators appreciate the difficulty that consumers encounter in conducting a full and proper registration check using the current system,” it says, noting that the current system is very complicated and necessitates the search of several databases. It also requires the consumer to know the registered name of the firm, although this may not be the business name the consumer knows, it notes. Additionally, FAIR Canada questions the CSA’s assertion that “registration status or category is more important than a title”; noting that it does not believe that the average investor knows enough about registration categories to understand whether a firm or individual is selling investments that they are qualified to sell, or to provide advice. The investor advocacy group suggests that regulators “need to provide a single, national comprehensive background check that Canadians can easily use to check the background, registration status, proficiency and disciplinary history of registrants.” It says this system should include information from the self-regulatory organizations, the Investment Industry Regulatory Organization of Canada (IIROC) and Mutual Fund Dealers Association of Canada (MFDA). And, it points to the U.S. Financial Industry Regulatory Authority’s (FINRA) BrokerCheck and IIROC’s AdvisorReport as more comprehensive and accessible databases. “We recommend that Canadian regulators look to these systems as examples,” it says; adding that they should also consult with investors to inform the design of such a system. “The provision of a simpler, more user-friendly interface for consumers to check the registration of any person or firm who sells securities or offers investment advice will assist consumers in performing the necessary checks to ensure that the firm or individual is appropriately registered,” it says. “We believe that Canadian securities regulators must provide an accessible and user-friendly system in the interests of investor protection.” Keywords Registration,  Investor protectionCompanies Canadian Securities Administrators, FAIR Canada Biden’s pick for SEC flags trading-app gimmicks for scrutiny James Langton read more

“De Lawd is My Shepherd” Restored in Spain and Returned to the National Gallery in Jamaica

first_imgRelated“De Lawd is My Shepherd” Restored in Spain and Returned to the National Gallery in Jamaica Related“De Lawd is My Shepherd” Restored in Spain and Returned to the National Gallery in Jamaica “De Lawd is My Shepherd” Restored in Spain and Returned to the National Gallery in Jamaica UncategorizedJune 28, 2008 Related“De Lawd is My Shepherd” Restored in Spain and Returned to the National Gallery in Jamaicacenter_img FacebookTwitterWhatsAppEmail The Osmond Watson painting, “De Lawd is My Shepherd”, considered to be a Jamaican masterpiece, has been restored in Spain and was today handed back to the Honourable Olivia “Babsy’ Grange, Minister of Information, Culture, Youth and Sports (MICYS) to resume its place in the National Gallery of Jamaica.Making the presentation to Minister Grange at ceremony at the National Gallery was the Spanish Ambassador to Jamaica His Excellency, Jesus Silva.Ambassador Silva’s assistance had been sought by the National Gallery to identify someone to professionally restore the painting after it was accidentally damaged last year November.Professor Sanchez Barrega, a well known restorer in Spain was contacted by the Ambassador and the professor agreed to undertake the restoration himself free of cost as a donation to the National Gallery and the people of Jamaica.Professor Sanchez Barrega, who was present at today’s ceremony, said he was pleased to undertake the restoration, describing it an intricate operation. He said he was thrilled to come to the assistance of Jamaica in this way.The professor has expressed a willingness to train a Jamaican to undertake restoration at the most sophisticated levels.Minister Grange thanked Ambassador Silva for what she termed, “this passionate cultural and artistic exchange.” She said the relationship between Jamaica and Spain was not based solely on the tourism industry but there was also a cultural relationship built on mutual respect and admiration.According to the Minister, both Jamaica and Spain, “punch above their weight in culture – in music, art, dance, storytelling and in general a creative approach to life that is evident in all of their citizens.”“De Lawd is My Shepherd” was acquired by the Institute of Jamaica and was one of a group of paintings and sculpture transferred to the National Gallery on its establishment in 1974. The painter and sculptor Osmond Watson, described as a defining figure in post-Independence Jamaican art, died in 2005 at the age of 71. Advertisementslast_img read more

House Begins Debate on Sexual Offences Act

first_imgRelatedHouse Begins Debate on Sexual Offences Act RelatedHouse Begins Debate on Sexual Offences Act House Begins Debate on Sexual Offences Act ParliamentJanuary 29, 2009 RelatedHouse Begins Debate on Sexual Offences Actcenter_img FacebookTwitterWhatsAppEmail Debate on the Sexual Offences Act 2008, which seeks to bring under one umbrella, the various laws relating to rape, incest and other sexual offences, began in the House of Representatives yesterday (Jan. 27).The Bill repeals the Incest (Punishment) Act and several provisions of the Offences Against the Person Act relating to rape and other sex crimes.Prime Minister, Bruce Golding, who opened the debate, stated that the legislation is one that has been “anxiously awaited, strenuously advocated for and extensively deliberate on.”“This Bill has been long in coming, it actually commenced in 1995 when separate Bills seeking to amend the Offences Against the Person Act and the Incest (Punishment) Act were brought to Parliament. They sought to expand the scope and the circumstances in which rape was committed,” Mr. Golding said.According to the Memorandum of Objects and Reasons of the Act, the Bill provides for a statutory definition of rape.“In this new Bill, we have sought to put beyond any doubt, any ambiguity about what sexual intercourse is,” Mr Golding stated. “So many times, persons were charged for rape and … were acquitted because people were able to find a way through this ambiguity, when a grievous assault had, in fact, been committed against a person. Because of the lack of clarity in the law, juries were reluctant to hand down guilty verdicts and judges might have been constrained to give certain directions to the jury because of what the law provided,” he explained.Other areas covered in the Bill include martial rape, specifying the circumstances in which such rape may be committed.Mr. Golding said that caution had to be exercised to avoid abuse of the law, especially in cases where relationships become turbulent and “perhaps, for a moment, there are feelings of vindictiveness that can find their expression in abusing a provision. Care had to be taken to ensure that marital rape was confined to particular circumstances.”According to the Bill, a husband commits the offence of rape against his wife, if he has sexual intercourse with his wife without her consent, and knowing that she does not consent to sexual intercourse, or recklessly not caring whether or not she consents.The Act also provides for the establishment of a Sex Offenders Registry, to be maintained by the Commissioner of Corrections, which will contain a list of sex offenders, to be known as the Offenders Register.The register will record every sexual offence conviction and released convicts are required to report in person, within three days of release, to the Registry. “You have to report to the Registry every time you leave the island. If you are changing your address, you have to report to the Registry within 14 days of change of address and in any case, you have to report to the Registry at least once a year and this is mandatory,” Mr. Golding told the House.Meanwhile, in her comments, Leader of the Opposition, Portia Simpson Miller, expressed support for the provisions to the Bill.“The outcomes represented in this Bill, represent a continuing journey and they have come about as a result of the selflessness of several individuals, various groups and institutions stretching back to the early 1990s,” Mrs. Simpson Miller said.Debate on the legislation will continue next Tuesday (Feb. 3) in the House of Representatives. Advertisementslast_img read more

News Roundup: Schwarzenegger sets teenage activist up with Tesla, Chevy unveils C8 convertible and more

first_img We encourage all readers to share their views on our articles using Facebook commenting Visit our FAQ page for more information. Trending in Canada Welcome to our weekly round-up of the biggest breaking stories on from this past week. Get caught up and ready to get on with the weekend, because it’s hard keeping pace in a digital traffic jam.Here’s what you missed while you were away.When Arnold met GretaWhen Arnold Schwarzenegger was introduced to 16-year-old climate activist Greta Thunberg at a European environmental summit earlier this year, he was thoroughly impressed. (Join the club, Arnold.) Buy It! Princess Diana’s humble little 1981 Ford Escort is up for auction An engagement gift from Prince Charles, the car is being sold by a Princess Di “superfan” See More Videos COMMENTSSHARE YOUR THOUGHTS The Rolls-Royce Boat Tail may be the most expensive new car ever And then, when he learned she’d be making a North American tour, he offered to set his new friend up with one of the greenest ways to get around: a Tesla Model 3. Thunberg travelled to Montreal to participate in the climate strike along with approximately 500,000 others, and is continuing on to other events elsewhere in North America. 70-year-old B.C. driver given ticket for having cell phone in cup holderWhere do you keep your cell phone when you’re driving? Obviously, it’s illegal to hold it in your hand and use it – that’s distracted driving – but one senior citizen in B.C. was shocked to receive a ticket this week for having her smartphone charging in a cup holder. Randi Kramer, who’s had a clean driving record for the last 50 years or so, was issued a $368 ticket for distracted driving, despite not being distracted by her phone at all. Kramer plans to fight the ticket and her story has already got the attention of a local lawyer. The new C8 convertible arrives with folding hardtopThe 2020 Chevy Corvette Stingray was unveiled this week, and unlike the initial C8 launch that nearly broke the internet earlier this summer, there’s not so much to report on. The new model will be available with a folding hardtop only, and be powered by the same plant as the coupe: a 6.2-litre 490-horsepower V8. Chevy chose to reveal the convertible at the Kennedy Space Center’s Rocket Garden in Orlando, Florida as a nod to all the astronauts who’ve driven ‘Vettes over the years. The 2020 Corvette convertible will start at $78,998 when it arrives in Canada next spring. Watch Tesla owners damage their cars using the new Smart Summon featureA new software update downloaded into Teslas around the world last weekend, teaching the electric vehicles a highly anticipated new trick. Smart Summon automatically pilots empty cars across parking lots or driveways to their drivers, who summon them with the press of a button on an app. But despite the word “Smart” being right there in the name, and Tesla officially reminding driver they “are still responsible for [their] car and must monitor it and its surroundings at all times,” the new feature has occasionally hit a few snags. Or, more accurately, other vehicles and garage doors. Check out some of the Smart Summon fails caught on camera and already making the rounds online. Russian YouTuber tests how many spokes your car wheel actually needsHow many spokes is enough spokes? Sure, all of them would be ideal, but when push came to shove, how many could you still drive with? Like, if you literally pushed and shoved (or cut) the spokes off the wheels, like this Russian YouTuber did, how far would you get? Turns out, pretty far! center_img advertisement The Garage 54 YouTube channel, which is dedicated to these kind of automotive “torture tests,” fits an old car with a bunch of tires with a varying number of the alloy spokes removed, and basically drives around on them until they break. The language dubbing is bearable, but the video itself is highly entertaining.  PlayThe Rolls-Royce Boat Tail may be the most expensive new car everPlay3 common new car problems (and how to prevent them) | Maintenance Advice | Driving.caPlayFinal 5 Minivan Contenders | Driving.caPlay2021 Volvo XC90 Recharge | Ministry of Interior Affairs | Driving.caPlayThe 2022 Ford F-150 Lightning is a new take on Canada’s fave truck | Driving.caPlayBuying a used Toyota Tundra? Check these 5 things first | Used Truck Advice | Driving.caPlayCanada’s most efficient trucks in 2021 | Driving.caPlay3 ways to make night driving safer and more comfortable | Advice | Driving.caPlayDriving into the Future: Sustainability and Innovation in tomorrow’s cars | virtual panelPlayThese spy shots get us an early glimpse of some future models | Trending Videos RELATED TAGSNews ‹ Previous Next ›last_img read more

Less than half of new units meeting city affordability rules

first_imgHomeNewsLess than half of new units meeting city affordability rules May. 14, 2018 at 11:00 amNewsLess than half of new units meeting city affordability rulesMatthew Hall3 years agodaily pressNewsSanta Monicasanta monica daily presssanta monica news Santa Monica has failed to meet its own affordable housing goals for the third consecutive year, building less than half of the aimed for affordable units.According to a report on Propositions R and I presented to the city last week, only 13 percent of the residences built last year were considered affordable. The City Charter requires 30 percent of new construction be affordable but developers have failed to meet that measurement for several years.The annual report measures the number of housing units completed, in construction and approved in a given year. While the charter only governs units completed, staff said the additional data shows what’s likely to happen down the line and helps account for the uneven pace of construction over the years.This year 100 residences were completed (13 affordable/13 percent), 586 units were under construction (118 affordable/20 percent) and 386 were approved (70 affordable/18 percent). In total the 16/17 year tracked 1,072 units (201 affordable/19 percent).The report tracks three stats, the number of affordable units created, compliance with affordability requirements by tenants and limits on the number of units the City can help finance. While the first measure fell short, affordability requirements are at a 99 percent compliance rate and the City was within its funding limits.Proposition R was passed by local voters in 1990 as an amendment to the City Charter. It requires thirty percent of all multifamily housing completed in each fiscal year be affordable to and occupied by low- and moderate-income households. Of that housing, at least one-half of the total affordable housing completed be affordable for and occupied by low-income households. The measurement is taken citywide and the charter doesn’t mandate construction on a project-by-project basis. Instead, several programs are in place to encourage the development of affordable housing including some requirements on specific projects, city-wide development standards and fiscal support for affordable housing from the City.The terms of the charter could be met by a 100 percent affordable housing project offsetting for-profit development that had less than 30 percent of their units designated affordable but the passage of the Downtown Community Plan changed the rules for some projects.According to the DCP projects in the Downtown must set aside up to 35 percent of their total units as affordable housing depending on the size and location of the project. Under the rules, projects of less than 50 feet have a 20 percent requirement for onsite housing and 25 percent for offsite. The percentages increase by one percent per two foot in height and any project between 70 – 84 feet have to provide 30 percent onsite or 35 percent offsite.Developers have the option to building housing on site as part of their project, build affordable housing offsite in a standalone development, pay fees in lieu of construction or donate land to the City or a nonprofit that builds affordable housing.In Fiscal Year 16/17, eight developments were completed. Four developments provided a total of 13 affordable residences while the rest paid a combined $1,247,872 in fees.This is the third consecutive year housing production has failed to meet the goal, a situation staff attribute to a lack of funding. According to the report, the primary problem is the loss of Redevelopment money when voters chose to dissolve local Redevelopment Agencies in 2012.“Without City funding, meeting the requirements of Proposition R has been a challenge, as nearly two-thirds of the affordable housing constructed in the past 23 years was funded with loans from City housing trust funds,” said the report.The Charter has no penalties for failing to meet the housing goals but does mandate Council should take action to meet the provisions in the future.According to the report, City Hall is attempting to fill the funding gap with property tax revenue ($1.2 million per year) that previously went to the redevelopment agency, one time money from land sales and profit participation agreements, repayment of loans made to the now-defunct redevelopment agency and an increase in the Transaction and Use Tax (TUT) by one-half percent, half of which (estimated at $8 million per year) is dedicated to affordable housing.Staff said the current shortfalls are the tail end of the crisis caused by eliminating redevelopment money and the new funding sources should cover the gap for several years allowing more affordable housing to be built in the coming years.According to the report, about 38 percent of all housing built since adopting Proposition R meet the affordability [email protected] Tags :daily pressNewsSanta Monicasanta monica daily presssanta monica newsshare on Facebookshare on Twitteradd a commentNew Chief seeks to hire more officers to combat rising crime ratePolice investigating a pair of gun crimesYou Might Also LikeFeaturedNewsBobadilla rejects Santa Monica City Manager positionMatthew Hall10 hours agoNewsCouncil picks new City ManagerBrennon Dixson21 hours agoFeaturedNewsProtesting parents and Snapchat remain in disagreement over child protection policiesClara Harter21 hours agoFeaturedNewsDowntown grocery to become mixed use developmenteditor21 hours agoNewsBruised but unbowed, meme stock investors are back for moreAssociated Press21 hours agoNewsWedding boom is on in the US as vendors scramble to keep upAssociated Press21 hours agolast_img read more

India’s RCom, Aircel to close merger in July – report

first_img Asia Tags Joseph Waring Previous ArticleConsistel nears $1B funding goal for Singapore’s 4th mobile licenceNext ArticleVodafone and Afrimax to bring 4G to Zambia HomeAsiaNews India’s RCom, Aircel to close merger in July – report India adds detail on network equipment restrictions WhatsApp takes more heat in India India’s fourth largest operator Reliance Communications (RCom) and smaller rival Aircel, which have been in merger talks since December, reportedly will close the deal within the next month, completing the country’s first merger between local players.The two operators are finalising the commercial and legal terms, the Economic Times reported. RCom and Aircel’s majority owner Maxis reportedly agreed earlier in the year to a 50:50 ownership structure if a deal was reached. The two operators last month extended the exclusivity period for talks by 30 days to 22 June, following “substantial progress”.A merger would give the joint entity about 188 million mobile connections, pushing it ahead of current number three Idea Cellular, which has nearly 174 million connections, but slightly behind number two Vodafone India with 197 million. Market leader Bharti Airtel has about 250 million connections. RCom has nearly a 10 per cent market share, while Aircel has an 8.5 per cent share, according to GSMA Intelligence.RCom is expected to spin off its wireless unit and then merge it with Aircel into a separate entity that will operate under a new brand name and not be listed for the first few years, the Times reported. RCom’s tower and overseas arms would remain part of the company.According to the Times, RCom and Aircel will each transfer INR14 billion ($208 million) of their debt into the wireless entity. Russia’s Sistema will hold 10 per cent in the listed RCom (RCom last year also struck a deal to acquire Sistema Shyam Teleservices, for about $690 million).The Aircel merger will give RCom an additional 89 million customers and INR15 billion in annual revenue.As part of a raft of cross-operator deals since the regulator eased spectrum trading and sharing rules last year, RCom and mobile newcomer Reliance Jio in January finalised a spectrum sharing and trading alliance that will see RCom sell 800MHz spectrum in nine regions to Jio and both share bandwidth in the same band in 17 service areas.In April Aircel agreed to sell Airtel 4G spectrum in eight service regions for INR35 billion, which will give it a nationwide 4G footprint to match Jio’s pan-India coverage. The sale will enable Aircel to reduce its INR180 billion debt by about INR40 billion ahead of its planned merger with RCom.center_img India to shun China vendors in 5G trials Author Joseph Waring joins Mobile World Live as the Asia editor for its new Asia channel. Before joining the GSMA, Joseph was group editor for Telecom Asia for more than ten years. In addition to writing features, news and blogs, he… Read more Related AddThis Sharing ButtonsShare to LinkedInLinkedInLinkedInShare to TwitterTwitterTwitterShare to FacebookFacebookFacebookShare to MoreAddThisMore 13 JUN 2016 AircelIndiamergerRcomlast_img read more

14 patients awaiting admission at LUH this morning

first_img Pregnant women can receive Covid vaccine at LYIT’s vaccination centre 14 patients awaiting admission at LUH this morning Further drop in people receiving PUP in Donegal 75 positive cases of Covid confirmed in North Google+ Twitter Gardai continue to investigate Kilmacrennan fire WhatsApp Facebook Twitter Facebook RELATED ARTICLESMORE FROM AUTHORcenter_img Pinterest WhatsApp By News Highland – April 11, 2017 Lárionad Acmhainní Nádúrtha CTR to take part in new research project Google+ News There were 14 patients awaiting admission at Letterkenny University Hospital this morning, 8 of them on Emergency Department trolleys. That’s up slightly on yesterday’s figure of 11.The INMO says nationally, there were 417 people awaiting beds this morning.Limerick University Hospital was the worst affected with a total of 42. Pinterest Previous articleBus Eireann dispute goes to the Labour Court as WRC talks break downNext articleDerry councillor raises road safety concerns at Grangemore and Ardgrange News Highland LUH still not ready to restore IT systemslast_img read more

Man and woman charged after heroin and cannabis are seized in Letterkenny

first_imgHomepage BannerNews Facebook Twitter By admin – February 14, 2016 Pinterest Google+ A man and woman in their 40s and 30s respectively are due before Letterkenny District Court in March, after they were arrested and charged with possession of heroin and cannabis on Friday night.Gardai say €1,700 worth of heroin was discovered along with an estimated €20,000 worth of ca\nnabis resin.The drugs were found during a planned search of a house in the Long Lane area of Letterkenny.A man and woman were subsequently arrested and charged. They were released bail, to appear in court next month. Previous articleAthletics glory for Donegal runnersNext articleArlene Arkinson inquest overshadowed by row over withheld files admin RELATED ARTICLESMORE FROM AUTHOR Pinterest Hospitalisations rise as Donnelly suggests masks will stay ’til autumn Man and woman charged after heroin and cannabis are seized in Letterkennycenter_img 45 new social homes to be built in Dungloe WhatsApp Facebook Google+ Twitter WhatsApp Donegal hoteliers enjoy morale boost as bookings increase Consultation launched on proposal to limit HGV traffic in Clady Disruption to cancer service will increase mortality – Oncologist Journey home will be easier – Paul Hegartylast_img read more